Hydroxypropyl methylcellulose (HPMC) is a semi-synthetic, inert, and water-soluble polymer derived from cellulose. Its chemical structure includes methoxy (-OCH₃) and hydroxypropyl (-CH₂CHOHCH₃) groups attached to the cellulose backbone. It appears as a white to off-white powder and forms a gel or solution when mixed with water.
HPMC is used in food, pharmaceutical, and industrial applications. In food, it functions as a thickener, emulsifier, stabilizer, and film-forming agent (E464). It is commonly found in sauces, dressings, bakery products, and coatings.
In pharmaceuticals, HPMC is used as a tablet binder, film coating, and controlled-release matrix in oral drug formulations. It helps control drug release rate and improves tablet stability. It is also used in eye drops as a lubricant.
In industrial use, HPMC is included in construction materials (e.g., tile adhesives, plasters) for water retention and improved workability. It is also used in cosmetics, detergents, and paints for its thickening and stabilizing properties.
